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1.4 ångström crystal structure of ABC transporter glutathione-binding protein gsht from streptococcus pneumoniae strain canada MDR_19A in complex with glutathione

Analyse 1.4 ångström crystal structure of ABC transporter glutathione-binding protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4EQ9
Type: protein
Length: 240 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ABC transporter substrate-binding protein-amino acid transport
UniProt: Q8DRG2
Ligands: GSH
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ABC transporter substrate-binding protein-amino acid transport	protein	240	37% helix, 23% strand	Q8DRG2

Ligands and binding sites

GSH · Glutathione · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	367	0.74	0.85	49	GSH

Compared structures

4EQ9 · 1.4 Angstrom Crystal Structure of ABC Transporter Glutathione-Binding Protein GshT from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DRG2
Elsewhere: RCSB PDB 4EQ9 · PDBe 4EQ9 · UniProt Q8DRG2

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