Research workbench
Atomic structure of the ruvc resolvase: a holliday junction-specific endonuclease from E. COLI
Analyse Atomic structure of the ruvc resolvase: a holliday junction-specific… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HJR
- Type
- protein
- Length
- 632 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Holliday junction resolvase (ruvc)
- EC
- 3.1.22.4
- UniProt
- P0A814
- Pockets
- 10 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Holliday junction resolvase (ruvc) (EC 3.1.22.4) | protein | 158 | 42% helix, 24% strand | P0A814 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 330 | 0.71 | 0.84 | 37 | empty |
| 2 | 186 | 0.54 | 0.78 | 25 | empty |
| 3 | 226 | 0.52 | 0.76 | 34 | empty |
| 4 | 68 | 0.50 | 0.85 | 17 | empty |
| 5 | 85 | 0.48 | 0.82 | 17 | empty |
Interfaces
3 interfaces between chains.
- B–D · 980 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 979 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 489 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 1HJR · Atomic structure of the ruvc resolvase: a holliday junction-specific endonuclease from E.… · the same entry in another collection · chain A against A, TM-score 1.00
- P0A814 · AlphaFold monomer V2.0 prediction for crossover junction endodeoxyribonuclease ruvc… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A814
- Elsewhere: RCSB PDB 1HJR · PDBe 1HJR · UniProt P0A814
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