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Crystal structure of the ubl domain of BAG6

Analyse Crystal structure of the ubl domain of BAG6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4EEW
Type: protein
Length: 149 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Large proline-rich protein BAG6
UniProt: P46379
Pockets: 1 · best druggability 0.65

Structure

x-ray diffraction · 2 distinct chains · 26% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Large proline-rich protein BAG6	protein	74	26% helix, 42% strand	P46379
B	Large proline-rich protein BAG6	protein	75	25% helix, 41% strand	P46379

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	312	0.65	0.81	34	empty

Interfaces

1 interface between chains.

A–B · 188 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

4EEW · Crystal structure of the Ubl domain of BAG6 · the same entry in another collection · chain A against A, TM-score 1.00
P46379 · AlphaFold monomer V2.0 prediction for large proline-rich protein BAG6 (P46379) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P46379
Elsewhere: RCSB PDB 4EEW · PDBe 4EEW · UniProt P46379

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