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Crystal structure of a leucine-rich repeat protein (BT_0210) from bacteroides thetaiotaomicron vpi-5482 at 2.80 a resolution

Analyse Crystal structure of a leucine-rich repeat protein (BT_0210) from bacteroides… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ECN
Type: protein
Length: 838 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Leucine-rich repeat protein
UniProt: Q8ABA0
Ligands: NA, CL
Pockets: 7 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Leucine-rich repeat protein	protein	838	15% helix, 28% strand	Q8ABA0

Ligands and binding sites

NA · Sodium ion · metal · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	306	0.55	0.76	43	empty
2	306	0.54	0.75	30	empty
3	208	0.50	0.76	34	empty
4	119	0.45	0.78	29	empty
5	69	0.44	0.82	18	empty

Modifications

Observed in the structure: 17 modified (engineered).

Compared structures

4ECN · Crystal structure of a leucine-rich repeat protein (BT_0210) from Bacteroides… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8ABA0
Elsewhere: RCSB PDB 4ECN · PDBe 4ECN · UniProt Q8ABA0

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