Research workbench
Crystal structure of the ectodomain of a receptor like kinase
Analyse Crystal structure of the ectodomain of a receptor like kinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4EBY
- Type
- protein
- Length
- 200 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chitin elicitor receptor kinase 1
- UniProt
- A8R7E6
- Ligands
- NAG, BMA
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 21% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chitin elicitor receptor kinase 1 | protein | 200 | 21% helix, 21% strand | A8R7E6 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains A
- BMA · beta-D-mannopyranose · sugar
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 198 | 0.53 | 0.78 | 25 | empty |
| 2 | 82 | 0.32 | 0.73 | 16 | empty |
| 3 | 58 | 0.26 | 0.73 | 18 | empty |
Modifications
Observed in the structure: 5 glycan, 3 disulfide (N-glycosylation, disulfide).
Compared structures
- 4EBY · Crystal structure of the ectodomain of a receptor like kinase · the same entry in another collection · chain A against A, TM-score 1.00
- A8R7E6 · AlphaFold monomer V2.0 prediction for chitin elicitor receptor kinase 1 (A8R7E6) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8R7E6
- Elsewhere: RCSB PDB 4EBY · PDBe 4EBY · UniProt A8R7E6
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