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Crystal structure of 16S rRNA methyltransferase rsme from E.COLI

Analyse Crystal structure of 16S rRNA methyltransferase rsme from E.COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4E8B
Type
protein
Length
242 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ribosomal RNA small subunit methyltransferase E
EC
2.1.1.193
UniProt
P0AGL7
Pockets
2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosomal RNA small subunit methyltransferase E (EC 2.1.1.193)protein24231% helix, 26% strandP0AGL7

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12070.540.7823empty
2620.300.7412empty

Compared structures

  • 4E8B · Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli · the same entry in another collection · chain A against A, TM-score 1.00
  • P0AGL7 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase E… · a predicted model of the same protein · chain A against A, TM-score 0.98

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