Research workbench
Solution structure of LNA3:RNA hybrid
Analyse Solution structure of LNA3:RNA hybrid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HHX
- Type
- DNA + RNA
- Length
- 18 nucleotides
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5- D(*CP*+TP*GP*AP*+TP*AP*+TP*GP*C) -3; 5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3
- Pockets
- 1 · best druggability 0.23
Structure
solution nmr · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5- D(*CP*+TP*GP*AP*+TP*AP*+TP*GP*C) -3 | dna | 9 | — | — |
| B | 5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3 | rna | 9 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.23 | 0.73 | 10 | empty |
Interfaces
1 interface between chains.
- A–B · 420 Ų buried · 49 hydrogen bonds · nucleic-nucleic
Modifications
Observed in the structure: 3 modified (nucleotide modification).
Compared structures
- 1HHX · Solution structure of LNA3:RNA hybrid · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1HHX · PDBe 1HHX
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