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The crystal structure of a short chain dehydrogenase family protein from francisella tularensis subsp. tularensis schu S4

Analyse The crystal structure of a short chain dehydrogenase family protein from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4E4Y
Type: protein
Length: 242 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Short chain dehydrogenase family protein
EC: 1.-.-.-
UniProt: Q5NG43
Ligands: SO4
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Short chain dehydrogenase family protein (EC 1.-.-.-)	protein	242	46% helix, 20% strand	Q5NG43

Ligands and binding sites

SO4 · Sulfate ion · ion · 5 copies · chains A
GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	521	0.76	0.83	49	SO4, GOL
2	59	0.29	0.74	18	empty

Modifications

Observed in the structure: 3 modified (engineered).

Compared structures

4E4Y · The crystal structure of a short chain dehydrogenase family protein from Francisella… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5NG43
Elsewhere: RCSB PDB 4E4Y · PDBe 4E4Y · UniProt Q5NG43

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