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Solution structure of LNA1:RNA hybrid

Analyse Solution structure of LNA1:RNA hybrid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1HHW
Type
DNA + RNA
Length
18 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5- D(*CP*TP*GP*AP*+TLNP*AP*TP*GP*C) -3; 5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A5- D(*CP*TP*GP*AP*+TLNP*AP*TP*GP*C) -3dna9——
B5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3rna9——

Interfaces

1 interface between chains.

  • A–B · 444 Ų buried · 44 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

  • 1HHW · Solution structure of LNA1:RNA hybrid · the same entry in another collection · chain A against A, TM-score 1.00

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