Research workbench

Crystal structure of the helicobacter pylori caga oncoprotein

Analyse Crystal structure of the helicobacter pylori caga oncoprotein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4DVY
Type: protein
Length: 656 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytotoxicity-associated immunodominant antigen
UniProt: P55980
Pockets: 7 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 63% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
P	Cytotoxicity-associated immunodominant antigen	protein	656	63% helix, 11% strand	P55980

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	467	0.61	0.76	40	empty
2	307	0.60	0.78	38	empty
3	139	0.58	0.83	24	empty
4	401	0.57	0.74	38	empty
5	160	0.51	0.78	26	empty

Compared structures

4DVY · Crystal structure of the Helicobacter pylori CagA oncoprotein · the same entry in another collection · chain P against P, TM-score 1.00
P55980 · AlphaFold monomer V2.0 prediction for cytotoxicity-associated immunodominant antigen… · a predicted model of the same protein · chain P against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55980
Elsewhere: RCSB PDB 4DVY · PDBe 4DVY · UniProt P55980

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.