Research workbench
The structure of the macrophage migration inhibitory factor from trichinella spiralis.
Analyse The structure of the macrophage migration inhibitory factor from trichinella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HFO
- Type
- protein
- Length
- 678 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Migration inhibitory factor
- UniProt
- Q9Y063
- Pockets
- 8 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Migration inhibitory factor | protein | 113 | 39% helix, 31% strand | Q9Y063 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 545 | 0.80 | 0.86 | 59 | empty |
| 2 | 517 | 0.79 | 0.86 | 52 | empty |
| 3 | 69 | 0.63 | 0.91 | 15 | empty |
| 4 | 52 | 0.52 | 0.88 | 16 | empty |
| 5 | 56 | 0.50 | 0.86 | 16 | empty |
Interfaces
6 interfaces between chains.
- A–C · 1148 Ų buried · 21 hydrogen bonds · protein-protein
- E–F · 1138 Ų buried · 20 hydrogen bonds · protein-protein
- D–F · 1133 Ų buried · 22 hydrogen bonds · protein-protein
- B–C · 1119 Ų buried · 19 hydrogen bonds · protein-protein
- A–B · 1103 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 1HFO · The Structure of the Macrophage Migration Inhibitory Factor from Trichinella Spiralis. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y063
- Elsewhere: RCSB PDB 1HFO · PDBe 1HFO · UniProt Q9Y063
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.