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Structure of glutamate-GABA antiporter gadc
Analyse Structure of glutamate-GABA antiporter gadc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4DJI
- Type
- protein
- Length
- 973 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable GLUTAMATE/GAMMA-aminobutyrate antiporter
- UniProt
- P63235
- Pockets
- 14 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 63% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable GLUTAMATE/GAMMA-aminobutyrate antiporter | protein | 493 | 61% helix, 2% strand | P63235 |
| B | Probable GLUTAMATE/GAMMA-aminobutyrate antiporter | protein | 480 | 64% helix, 1% strand | P63235 |
Pockets
14 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 948 | 0.79 | 0.80 | 65 | empty |
| 2 | 274 | 0.79 | 0.90 | 46 | empty |
| 3 | 276 | 0.78 | 0.90 | 40 | empty |
| 4 | 59 | 0.70 | 0.97 | 20 | empty |
| 5 | 173 | 0.62 | 0.83 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 713 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63235
- Elsewhere: RCSB PDB 4DJI · PDBe 4DJI · UniProt P63235
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