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Crystal structure of an immunogenic protein from ehrlichia chaffeensis

Analyse Crystal structure of an immunogenic protein from ehrlichia chaffeensis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4DDD
Type: protein
Length: 300 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Immunogenic protein
UniProt: Q2GGH8
Ligands: CL
Pockets: 3 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Immunogenic protein	protein	300	41% helix, 23% strand	Q2GGH8

Ligands and binding sites

CL · Chloride ion · ion · chains A
EDO · 1,2-ethanediol · additive · 3 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	246	0.79	0.92	42	CL, GOL
2	52	0.42	0.83	19	empty
3	73	0.36	0.77	20	EDO

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4DDD · Crystal structure of an immunogenic protein from ehrlichia chaffeensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2GGH8
Elsewhere: RCSB PDB 4DDD · PDBe 4DDD · UniProt Q2GGH8

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