Research workbench
TETR(D) in complex with anhydrotetracycline and potassium
Analyse TETR(D) in complex with anhydrotetracycline and potassium in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4D7N
- Type
- protein
- Length
- 195 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetracycline repressor, class D
- UniProt
- A0A017KEE3
- Ligands
- TDC, K, CL
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetracycline repressor, class D | protein | 195 | 73% helix, 0% strand | A0A017KEE3 |
Ligands and binding sites
- TDC · 5A,6-anhydrotetracycline · ligand · chains A
- K · Potassium ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 308 | 0.64 | 0.80 | 36 | TDC, K |
| 2 | 65 | 0.28 | 0.73 | 17 | empty |
Compared structures
- 4D7N · TetR(D) in complex with anhydrotetracycline and potassium · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A017KEE3
- Elsewhere: RCSB PDB 4D7N · PDBe 4D7N · UniProt A0A017KEE3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.