Research workbench
AKAP13 (akap-lbc) dh domain
Analyse AKAP13 (akap-lbc) dh domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4D0O
- Type
- protein
- Length
- 474 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- A-kinase anchor protein 13
- UniProt
- Q12802
- Pockets
- 3 · best druggability 0.83
Structure
x-ray diffraction · 2 distinct chains · 80% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | A-kinase anchor protein 13 | protein | 234 | 80% helix, 1% strand | Q12802 |
| B | A-kinase anchor protein 13 | protein | 240 | 80% helix, 1% strand | Q12802 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1136 | 0.83 | 0.84 | 90 | empty |
| 2 | 279 | 0.71 | 0.85 | 34 | empty |
| 3 | 50 | 0.28 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 680 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4D0O · AKAP13 (AKAP-Lbc) DH domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12802
- Elsewhere: RCSB PDB 4D0O · PDBe 4D0O · UniProt Q12802
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