Research workbench
Truncated tetramerization domain of zebrafish P53 (crystal form I)
Analyse Truncated tetramerization domain of zebrafish P53 (crystal form I) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4CZ5
- Type
- protein
- Length
- 118 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cellular tumor antigen P53
- UniProt
- G1K2L5
- Pockets
- 1 · best druggability 0.27
Structure
x-ray diffraction · 3 distinct chains · 56% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | Cellular tumor antigen P53 | protein | 29 | 55% helix, 24% strand | G1K2L5 |
| B | Cellular tumor antigen P53 | protein | 28 | 61% helix, 25% strand | G1K2L5 |
| C | Cellular tumor antigen P53 | protein | 32 | 53% helix, 22% strand | G1K2L5 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.27 | 0.74 | 13 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1375 Ų buried · 22 hydrogen bonds · protein-protein
- A–B · 1166 Ų buried · 19 hydrogen bonds · protein-protein
- A–D · 329 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 313 Ų buried · 7 hydrogen bonds · protein-protein
- B–D · 183 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4CZ5 · Truncated tetramerization domain of zebrafish p53 (crystal form I) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G1K2L5
- Elsewhere: RCSB PDB 4CZ5 · PDBe 4CZ5 · UniProt G1K2L5
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