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An intertwined homodimer of the PDZ homology domain of AHNAK2

Analyse An intertwined homodimer of the PDZ homology domain of AHNAK2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4CN0
Type
protein
Length
180 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein AHNAK2
UniProt
Q8IVF2
Ligands
K

Structure

x-ray diffraction · 2 distinct chains · 16% helix, 39% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein AHNAK2protein8717% helix, 40% strandQ8IVF2
BProtein AHNAK2protein9315% helix, 38% strandQ8IVF2

Ligands and binding sites

  • K · Potassium ion · metal · chains B
  • PG4 · Tetraethylene glycol · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 3861 Ų buried · 74 hydrogen bonds · protein-protein

Compared structures

  • 4CN0 · An intertwined homodimer of the PDZ homology domain of AHNAK2 · the same entry in another collection · chain A against A, TM-score 1.00

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