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The crystal structure of novel exo-type maltose-forming AMYLASE(PY04_0872) from pyrococcus sp. ST04
Analyse The crystal structure of novel exo-type maltose-forming AMYLASE(PY04_0872) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4CMR
- Type
- protein
- Length
- 1,192 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycosyl HYDROLASE/DEACETYLASE family protein
- UniProt
- I3RE04
- Pockets
- 6 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycosyl HYDROLASE/DEACETYLASE family protein | protein | 597 | 50% helix, 15% strand | I3RE04 |
| B | Glycosyl HYDROLASE/DEACETYLASE family protein | protein | 595 | 49% helix, 16% strand | I3RE04 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 441 | 0.76 | 0.85 | 38 | empty |
| 2 | 450 | 0.75 | 0.84 | 40 | empty |
| 3 | 776 | 0.75 | 0.79 | 77 | empty |
| 4 | 52 | 0.69 | 0.98 | 19 | empty |
| 5 | 118 | 0.38 | 0.74 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 1145 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 34 modified, 2 disulfide (engineered, disulfide).
Compared structures
- 4CMR · The crystal structure of novel exo-type maltose-forming amylase(Py04_0872) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I3RE04
- Elsewhere: RCSB PDB 4CMR · PDBe 4CMR · UniProt I3RE04
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