Research workbench
Crystal structure of a tau class glutathione transferase 10 from glycine max
Analyse Crystal structure of a tau class glutathione transferase 10 from glycine max in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4CHS
- Type
- protein
- Length
- 430 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione S-transferase
- EC
- 2.5.1.18
- UniProt
- Q9FQE8
- Ligands
- GS8, ACN
- Pockets
- 4 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutathione S-transferase (EC 2.5.1.18) | protein | 215 | 60% helix, 9% strand | Q9FQE8 |
| B | Glutathione S-transferase (EC 2.5.1.18) | protein | 215 | 60% helix, 9% strand | Q9FQE8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 970 | 0.77 | 0.79 | 78 | GS8 |
| 2 | 117 | 0.42 | 0.77 | 20 | empty |
| 3 | 87 | 0.39 | 0.77 | 18 | empty |
| 4 | 56 | 0.29 | 0.75 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1086 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 4CHS · Crystal structure of a tau class glutathione transferase 10 from Glycine max · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9FQE8
- Elsewhere: RCSB PDB 4CHS · PDBe 4CHS · UniProt Q9FQE8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.