Research workbench
Crystal structure of the tir domain from the arabidopsis thaliana disease resistance protein RPS4
Analyse Crystal structure of the tir domain from the arabidopsis thaliana disease… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4C6R
- Type
- protein
- Length
- 648 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Disease resistance protein RPS4
- UniProt
- Q9XGM3
- Pockets
- 4 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Disease resistance protein RPS4 | protein | 162 | 55% helix, 14% strand | Q9XGM3 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 297 | 0.65 | 0.81 | 34 | empty |
| 2 | 50 | 0.47 | 0.85 | 14 | empty |
| 3 | 134 | 0.45 | 0.77 | 20 | empty |
| 4 | 65 | 0.29 | 0.74 | 15 | empty |
Interfaces
3 interfaces between chains.
- C–D · 350 Ų buried · 2 hydrogen bonds · protein-protein
- B–D · 288 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 11 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4C6R · Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9XGM3 · AlphaFold monomer V2.0 prediction for disease resistance protein RPS4 (Q9XGM3) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XGM3
- Elsewhere: RCSB PDB 4C6R · PDBe 4C6R · UniProt Q9XGM3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.