Research workbench
Structure of wildtype pii from S. elongatus at medium resolution
Analyse Structure of wildtype pii from S. elongatus at medium resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4C3M
- Type
- protein
- Length
- 270 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nitrogen regulatory protein P-II
- UniProt
- P0A3F4
- Pockets
- 5 · best druggability 0.72
Structure
x-ray diffraction · 3 distinct chains · 31% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nitrogen regulatory protein P-II | protein | 91 | 31% helix, 40% strand | P0A3F4 |
| B | Nitrogen regulatory protein P-II | protein | 89 | 31% helix, 38% strand | P0A3F4 |
| C | Nitrogen regulatory protein P-II | protein | 90 | 31% helix, 39% strand | P0A3F4 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.72 | 0.98 | 20 | empty |
| 2 | 221 | 0.64 | 0.83 | 35 | empty |
| 3 | 262 | 0.63 | 0.81 | 35 | empty |
| 4 | 228 | 0.63 | 0.82 | 34 | empty |
| 5 | 94 | 0.39 | 0.77 | 22 | empty |
Interfaces
3 interfaces between chains.
- A–C · 1110 Ų buried · 14 hydrogen bonds · protein-protein
- A–B · 1092 Ų buried · 15 hydrogen bonds · protein-protein
- B–C · 1063 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 4C3M · Structure of wildtype PII from S. elongatus at medium resolution · the same entry in another collection · chain A against A, TM-score 1.00
- P0A3F4 · AlphaFold monomer V2.0 prediction for nitrogen regulatory protein P-II (P0A3F4) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A3F4
- Elsewhere: RCSB PDB 4C3M · PDBe 4C3M · UniProt P0A3F4
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