Research workbench
Bacteroides thetaiotaomicron vpi-5482 mannosyl-6-phosphatase BT3783
Analyse Bacteroides thetaiotaomicron vpi-5482 mannosyl-6-phosphatase BT3783 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4C1R
- Type
- protein
- Length
- 1,068 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mannosyl-6-phosphatase
- UniProt
- Q8A183
- Ligands
- MG
- Pockets
- 9 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 21% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Mannosyl-6-phosphatase | protein | 267 | 21% helix, 33% strand | Q8A183 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 281 | 0.55 | 0.76 | 30 | empty |
| 2 | 296 | 0.53 | 0.75 | 36 | MG |
| 3 | 217 | 0.51 | 0.77 | 30 | empty |
| 4 | 54 | 0.49 | 0.85 | 15 | EDO |
| 5 | 85 | 0.39 | 0.77 | 18 | empty |
Interfaces
3 interfaces between chains.
- B–D · 1453 Ų buried · 29 hydrogen bonds · protein-protein
- A–C · 601 Ų buried · 5 hydrogen bonds · protein-protein
- A–B · 108 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4C1R · Bacteroides thetaiotaomicron VPI-5482 mannosyl-6-phosphatase Bt3783 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A183
- Elsewhere: RCSB PDB 4C1R · PDBe 4C1R · UniProt Q8A183
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