Research workbench
Sas-4 (dcpap) tcp domain in complex with a proline rich motif of ANA2 (dstil) of drosophila melanogaster
Analyse Sas-4 (dcpap) tcp domain in complex with a proline rich motif of ANA2 (dstil)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4BY2
- Type
- protein
- Length
- 464 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Anastral spindle 2, sas 4
- UniProt
- Q9XZ31, Q9VI72
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · 3 distinct chains · 0% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Anastral spindle 2, sas 4 | protein | 154 | 0% helix, 45% strand | Q9XZ31, Q9VI72 |
| B | Anastral spindle 2, sas 4 | protein | 155 | 0% helix, 44% strand | Q9XZ31, Q9VI72 |
| C | Anastral spindle 2, sas 4 | protein | 155 | 0% helix, 44% strand | Q9XZ31, Q9VI72 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 368 | 0.69 | 0.81 | 36 | EDO |
| 2 | 376 | 0.63 | 0.78 | 45 | empty |
| 3 | 254 | 0.52 | 0.76 | 29 | empty |
Interfaces
2 interfaces between chains.
- B–C · 873 Ų buried · 16 hydrogen bonds · protein-protein
- A–B · 521 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4BY2 · SAS-4 (dCPAP) TCP domain in complex with a Proline Rich Motif of Ana2 (dSTIL) of… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XZ31
- Every structure of UniProt Q9VI72
- Elsewhere: RCSB PDB 4BY2 · PDBe 4BY2 · UniProt Q9XZ31 · UniProt Q9VI72
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.