Research workbench
Crystal structure of a monomeric variant of murine chronophin (pyridoxal phosphate phosphatase)
Analyse Crystal structure of a monomeric variant of murine chronophin (pyridoxal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4BX0
- Type
- protein
- Length
- 287 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pyridoxal phosphate phosphatase
- EC
- 3.1.3.74, 3.1.3.3
- UniProt
- P60487
- Ligands
- MG
- Pockets
- 2 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyridoxal phosphate phosphatase (EC 3.1.3.74, 3.1.3.3) | protein | 287 | 41% helix, 20% strand | P60487 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.68 | 0.87 | 30 | empty |
| 2 | 61 | 0.30 | 0.75 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4BX0 · Crystal Structure of a Monomeric Variant of murine Chronophin (Pyridoxal Phosphate… · the same entry in another collection · chain A against A, TM-score 1.00
- P60487 · AlphaFold monomer V2.0 prediction for pyridoxal phosphate phosphatase (P60487) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60487
- Elsewhere: RCSB PDB 4BX0 · PDBe 4BX0 · UniProt P60487
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