Research workbench
Calmodulin in complex with strontium
Analyse Calmodulin in complex with strontium in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4BW7
- Type
- protein
- Length
- 283 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calmodulin
- UniProt
- P62158
- Ligands
- SR
- Pockets
- 3 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 63% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calmodulin | protein | 137 | 63% helix, 4% strand | P62158 |
| C | Calmodulin | protein | 146 | 62% helix, 4% strand | P62158 |
Ligands and binding sites
- SR · Strontium ion · metal · 9 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 169 | 0.50 | 0.78 | 19 | empty |
| 2 | 85 | 0.47 | 0.80 | 13 | empty |
| 3 | 76 | 0.45 | 0.80 | 12 | empty |
Interfaces
1 interface between chains.
- A–C · 525 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4BW7 · Calmodulin in complex with strontium · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62158
- Elsewhere: RCSB PDB 4BW7 · PDBe 4BW7 · UniProt P62158
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