Research workbench
Active mutant (Q365->C) of glucose 6-phosphate dehydrogenase from leuconostoc mesenteroides
Analyse Active mutant (Q365->C) of glucose 6-phosphate dehydrogenase from leuconostoc… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1H9B
- Type
- protein
- Length
- 485 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glucose 6-phosphate 1-dehydrogenase
- EC
- 1.1.1.49
- UniProt
- P11411
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glucose 6-phosphate 1-dehydrogenase (EC 1.1.1.49) | protein | 485 | 39% helix, 20% strand | P11411 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 313 | 0.61 | 0.79 | 45 | SO4 |
| 2 | 129 | 0.41 | 0.75 | 19 | empty |
| 3 | 61 | 0.33 | 0.76 | 13 | empty |
| 4 | 51 | 0.31 | 0.77 | 12 | empty |
| 5 | 73 | 0.30 | 0.72 | 17 | empty |
Compared structures
- 1H9B · Active mutant (Q365->C) of glucose 6-phosphate dehydrogenase from leuconostoc… · the same entry in another collection · chain A against A, TM-score 1.00
- P11411 · AlphaFold monomer V2.0 prediction for glucose-6-phosphate 1-dehydrogenase (P11411) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11411
- Elsewhere: RCSB PDB 1H9B · PDBe 1H9B · UniProt P11411
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.