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The IDAS:GEMININ heterodimeric parallel coiled-coil

Analyse The IDAS:GEMININ heterodimeric parallel coiled-coil in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4BRY
Type
protein
Length
138 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Geminin; Multicilin
UniProt
O75496, D6RGH6
Ligands
PO4

Structure

x-ray diffraction · 2 distinct chains · 92% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGemininprotein6993% helix, 0% strandO75496
BMulticilinprotein6991% helix, 0% strandD6RGH6

Ligands and binding sites

  • PO4 · Phosphate ion · ion · 2 copies · chains A, B
  • PG4 · Tetraethylene glycol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 1483 Ų buried · 19 hydrogen bonds · protein-protein

Compared structures

  • 4BRY · The Idas:Geminin heterodimeric parallel coiled-coil · the same entry in another collection · chain A against A, TM-score 1.00
  • O75496 · AlphaFold monomer V2.0 prediction for geminin (O75496) · a predicted model of the same protein · chain A against A, TM-score 0.80
  • D6RGH6 · AlphaFold monomer V2.0 prediction for multicilin (D6RGH6) · a predicted model of the same protein · chain B against A, TM-score 0.73

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