Research workbench
Crystal structure of hexameric HBC149 Y132A
Analyse Crystal structure of hexameric HBC149 Y132A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4BMG
- Type
- protein
- Length
- 855 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein
- UniProt
- P03147
- Pockets
- 9 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 59% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, E | Capsid protein | protein | 143 | 61% helix, 0% strand | P03147 |
| B, D, F | Capsid protein | protein | 142 | 58% helix, 0% strand | P03147 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 242 | 0.69 | 0.85 | 27 | empty |
| 2 | 212 | 0.66 | 0.84 | 35 | empty |
| 3 | 71 | 0.61 | 0.90 | 21 | empty |
| 4 | 122 | 0.60 | 0.85 | 25 | empty |
| 5 | 75 | 0.50 | 0.83 | 14 | empty |
Interfaces
7 interfaces between chains.
- C–D · 2065 Ų buried · 18 hydrogen bonds · protein-protein
- E–F · 1967 Ų buried · 20 hydrogen bonds · protein-protein
- A–B · 1941 Ų buried · 22 hydrogen bonds · protein-protein
- A–F · 582 Ų buried · 2 hydrogen bonds · protein-protein
- C–E · 521 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 4BMG · Crystal structure of hexameric HBc149 Y132A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03147
- Elsewhere: RCSB PDB 4BMG · PDBe 4BMG · UniProt P03147
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.