Research workbench
Crystal structure of germline antibody 36-65 in complex with peptide ppypawhapgni
Analyse Crystal structure of germline antibody 36-65 in complex with peptide… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4BH7
- Type
- protein
- Length
- 440 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Anti-ars murine germline monoclonal antibody 36-65; Dodecapeptide antigen
- Pockets
- 3 · best druggability 0.55
Structure
x-ray diffraction · 3 distinct chains · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Anti-ars murine germline monoclonal antibody 36-65 | protein | 214 | 6% helix, 49% strand | — |
| B | Anti-ars murine germline monoclonal antibody 36-65 | protein | 218 | 7% helix, 54% strand | — |
| P | Dodecapeptide antigen | protein | 8 | 0% helix, 0% strand | — |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 395 | 0.55 | 0.73 | 52 | empty |
| 2 | 61 | 0.30 | 0.75 | 19 | empty |
| 3 | 52 | 0.25 | 0.72 | 13 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1941 Ų buried · 17 hydrogen bonds · protein-protein
- B–P · 287 Ų buried · 4 hydrogen bonds · protein-protein
- A–P · 203 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 4BH7 · Crystal structure of germline antibody 36-65 in complex with peptide ppypawhapgni · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4BH7 · PDBe 4BH7
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