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FPR4 ppi domain

Analyse FPR4 ppi domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4BF8
Type: protein
Length: 117 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: FPR4
EC: 5.2.1.8
UniProt: Q06205
Pockets: 2 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 8% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	FPR4 (EC 5.2.1.8)	protein	117	8% helix, 42% strand	Q06205

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.32	0.75	12	empty
2	53	0.30	0.77	17	empty

Compared structures

4BF8 · Fpr4 PPI domain · the same entry in another collection · chain A against A, TM-score 1.00
Q06205 · AlphaFold monomer V2.0 prediction for FK506-binding protein 4 (Q06205) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q06205
Elsewhere: RCSB PDB 4BF8 · PDBe 4BF8 · UniProt Q06205

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