Research workbench

X-ray structure of zint from salmonella enterica in complex with zinc ion and peg

Analyse X-ray structure of zint from salmonella enterica in complex with zinc ion and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4AW8
Type: protein
Length: 186 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metal-binding protein zint
UniProt: A0A315GY36
Ligands: NA, ZN, SO4
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metal-binding protein zint	protein	186	29% helix, 31% strand	A0A315GY36

Ligands and binding sites

NA · Sodium ion · metal · 2 copies · chains A
ZN · Zinc ion · metal · chains A
SO4 · Sulfate ion · ion · 5 copies · chains A
PG6 · 1-(2-methoxy-ethoxy)-2-{2-[2-(2-methoxy-ethoxy]-ethoxy}-ethane · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	443	0.66	0.78	45	ZN, PG6

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4AW8 · X-ray structure of ZinT from Salmonella enterica in complex with zinc ion and PEG · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A315GY36
Elsewhere: RCSB PDB 4AW8 · PDBe 4AW8 · UniProt A0A315GY36

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.