Research workbench
Single particle electron microscopy of pilq dodecameric complexes from neisseria meningitidis.
Analyse Single particle electron microscopy of pilq dodecameric complexes from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4AV2
- Type
- protein
- Length
- 4,272 residues
- Chains
- 24
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type IV pilus biogenesis and competence protein pilq; Pilp protein
- UniProt
- Q70M91, Q7DD77
- Pockets
- 20 · best druggability 0.82
Structure
electron microscopy · 2 distinct chains · 21% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L | Type IV pilus biogenesis and competence protein pilq | protein | 274 | 26% helix, 33% strand | Q70M91 |
| M, N, O, P, Q, R, S, T, U, V, W, X | Pilp protein | protein | 82 | 5% helix, 56% strand | Q7DD77 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1086 | 0.82 | 0.83 | 114 | empty |
| 2 | 869 | 0.80 | 0.83 | 89 | empty |
| 3 | 1053 | 0.80 | 0.82 | 108 | empty |
| 4 | 580 | 0.76 | 0.82 | 65 | empty |
| 5 | 572 | 0.75 | 0.82 | 56 | empty |
Interfaces
24 interfaces between chains.
- J–K · 1824 Ų buried · 25 hydrogen bonds · protein-protein
- K–L · 1824 Ų buried · 26 hydrogen bonds · protein-protein
- C–D · 1823 Ų buried · 25 hydrogen bonds · protein-protein
- B–C · 1823 Ų buried · 25 hydrogen bonds · protein-protein
- A–B · 1823 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 4AV2 · Single particle electron microscopy of PilQ dodecameric complexes from Neisseria… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q70M91
- Every structure of UniProt Q7DD77
- Elsewhere: RCSB PDB 4AV2 · PDBe 4AV2 · UniProt Q70M91 · UniProt Q7DD77
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