Research workbench
Biomphalaria glabrata acetylcholine-binding protein type 1 (BGACHBP1)
Analyse Biomphalaria glabrata acetylcholine-binding protein type 1 (BGACHBP1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4AOD
- Type
- protein
- Length
- 1,025 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetylcholine-binding protein type 1
- Pockets
- 13 · best druggability 0.80
Structure
electron microscopy · 1 distinct chain · 8% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E | Acetylcholine-binding protein type 1 | protein | 205 | 8% helix, 48% strand | — |
Pockets
13 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 792 | 0.80 | 0.83 | 92 | empty |
| 2 | 806 | 0.80 | 0.83 | 85 | empty |
| 3 | 791 | 0.80 | 0.83 | 82 | empty |
| 4 | 575 | 0.77 | 0.83 | 70 | empty |
| 5 | 413 | 0.76 | 0.85 | 44 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1470 Ų buried · 52 hydrogen bonds · protein-protein
- B–C · 1468 Ų buried · 52 hydrogen bonds · protein-protein
- C–D · 1467 Ų buried · 52 hydrogen bonds · protein-protein
- D–E · 1466 Ų buried · 52 hydrogen bonds · protein-protein
- A–E · 1461 Ų buried · 52 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 disulfide (disulfide).
Compared structures
- 4AOD · Biomphalaria glabrata Acetylcholine-binding protein type 1 (BgAChBP1) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4AOD · PDBe 4AOD
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.