Research workbench
Structure of the ornithine carbamoyltransferase from mycoplasma penetrans with a P23 space group
Analyse Structure of the ornithine carbamoyltransferase from mycoplasma penetrans with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ANF
- Type
- protein
- Length
- 1,368 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ornithine carbamoyltransferase, catabolic
- EC
- 2.1.3.3
- UniProt
- Q8EVF5
- Pockets
- 14 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Ornithine carbamoyltransferase, catabolic (EC 2.1.3.3) | protein | 342 | 47% helix, 15% strand | Q8EVF5 |
Pockets
14 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 612 | 0.70 | 0.78 | 58 | empty |
| 2 | 536 | 0.69 | 0.79 | 51 | empty |
| 3 | 360 | 0.63 | 0.78 | 31 | empty |
| 4 | 377 | 0.62 | 0.78 | 33 | empty |
| 5 | 344 | 0.62 | 0.78 | 30 | empty |
Interfaces
2 interfaces between chains.
- A–C · 669 Ų buried · 7 hydrogen bonds · protein-protein
- B–D · 668 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 4ANF · Structure of the ornithine carbamoyltransferase from Mycoplasma penetrans with a P23… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8EVF5 · AlphaFold monomer V2.0 prediction for ornithine carbamoyltransferase, catabolic (Q8EVF5) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8EVF5
- Elsewhere: RCSB PDB 4ANF · PDBe 4ANF · UniProt Q8EVF5
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