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The crystal structure of mouse protein-Z dependent protease INHIBITOR(MZPI)

Analyse The crystal structure of mouse protein-Z dependent protease INHIBITOR(MZPI) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4AJT
Type
protein
Length
372 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein Z-dependent protease inhibitor
UniProt
Q8R121
Pockets
3 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 31% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein Z-dependent protease inhibitorprotein37233% helix, 31% strandQ8R121

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1570.660.9415empty
2690.410.8013empty
3580.340.7716empty

Compared structures

  • 4AJT · The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI) · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8R121 · AlphaFold monomer V2.0 prediction for protein Z-dependent protease inhibitor (Q8R121) · a predicted model of the same protein · chain A against A, TM-score 0.96

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