Research workbench
Structural basis of the DCP1:DCP2 mRNA decapping complex activation by EDC3 and SCD6
Analyse Structural basis of the DCP1:DCP2 mRNA decapping complex activation by EDC3 and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4A53
- Type
- protein
- Length
- 125 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- EDC3
- UniProt
- O94752
- Pockets
- 2 · best druggability 0.48
Structure
solution nmr · 1 distinct chain · 6% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | EDC3 | protein | 125 | 6% helix, 29% strand | O94752 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 283 | 0.48 | 0.73 | 40 | empty |
| 2 | 78 | 0.35 | 0.75 | 17 | empty |
Compared structures
- 4A53 · Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6 · the same entry in another collection · chain A against A, TM-score 1.00
- O94752 · AlphaFold monomer V2.0 prediction for enhancer of mRNA-decapping protein 3 (O94752) · a predicted model of the same protein · chain A against A, TM-score 0.48
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O94752
- Elsewhere: RCSB PDB 4A53 · PDBe 4A53 · UniProt O94752
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