Research workbench
Crystal structure of human mitochondrial enolase superfamily member 1 (ENOSF1)
Analyse Crystal structure of human mitochondrial enolase superfamily member 1 (ENOSF1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4A35
- Type
- protein
- Length
- 441 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mitochondrial enolase superfamily member 1
- EC
- 5.-.-.-
- UniProt
- Q7L5Y1
- Ligands
- MG
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitochondrial enolase superfamily member 1 (EC 5.-.-.-) | protein | 441 | 46% helix, 15% strand | Q7L5Y1 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 165 | 0.67 | 0.87 | 34 | empty |
Compared structures
- 4A35 · Crystal structure of human Mitochondrial enolase superfamily member 1 (ENOSF1) · the same entry in another collection · chain A against A, TM-score 1.00
- Q7L5Y1 · AlphaFold monomer V2.0 prediction for mitochondrial enolase superfamily member 1 (Q7L5Y1) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7L5Y1
- Elsewhere: RCSB PDB 4A35 · PDBe 4A35 · UniProt Q7L5Y1
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