Research workbench
Structure of the global transcription regulator fapr from staphylococcus aureus
Analyse Structure of the global transcription regulator fapr from staphylococcus aureus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4A0Y
- Type
- protein
- Length
- 302 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription factor fapr
- UniProt
- D6UB50
- Ligands
- CL
- Pockets
- 5 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription factor fapr | protein | 184 | 38% helix, 34% strand | D6UB50 |
| B | Transcription factor fapr | protein | 118 | 18% helix, 53% strand | D6UB50 |
Ligands and binding sites
- CL · Chloride ion · ion · 9 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.62 | 0.92 | 23 | CL |
| 2 | 53 | 0.57 | 0.90 | 17 | empty |
| 3 | 73 | 0.35 | 0.76 | 18 | empty |
| 4 | 89 | 0.33 | 0.73 | 14 | empty |
| 5 | 55 | 0.32 | 0.77 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1365 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 4A0Y · Structure of the global transcription regulator FapR from Staphylococcus aureus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D6UB50
- Elsewhere: RCSB PDB 4A0Y · PDBe 4A0Y · UniProt D6UB50
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.