Research workbench
Engineered 12-subunit bacillus subtilis TRP RNA-binding attenuation protein (trap)
Analyse Engineered 12-subunit bacillus subtilis TRP RNA-binding attenuation protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ZZQ
- Type
- protein
- Length
- 390 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription attenuation protein mtrb
- UniProt
- P19466
- Ligands
- TRP
- Pockets
- 6 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 62% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Transcription attenuation protein mtrb | protein | 65 | 0% helix, 62% strand | P19466 |
Ligands and binding sites
- TRP · Tryptophan · ligand · 12 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.76 | 0.98 | 22 | TRP |
| 2 | 93 | 0.76 | 0.98 | 22 | TRP |
| 3 | 91 | 0.76 | 0.98 | 21 | TRP |
| 4 | 91 | 0.75 | 0.97 | 21 | TRP |
| 5 | 81 | 0.75 | 0.98 | 21 | TRP |
Interfaces
8 interfaces between chains.
- D–E · 1082 Ų buried · 15 hydrogen bonds · protein-protein
- B–C · 1081 Ų buried · 16 hydrogen bonds · protein-protein
- E–F · 1081 Ų buried · 17 hydrogen bonds · protein-protein
- C–D · 1065 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 1054 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 3ZZQ · Engineered 12-subunit Bacillus subtilis trp RNA-binding attenuation protein (TRAP) · the same entry in another collection · chain F against F, TM-score 1.00
- P19466 · AlphaFold monomer V2.0 prediction for transcription attenuation protein mtrb (P19466) · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19466
- Elsewhere: RCSB PDB 3ZZQ · PDBe 3ZZQ · UniProt P19466
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.