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Crystal structure of STU0660 of streptococcus thermophilus

Analyse Crystal structure of STU0660 of streptococcus thermophilus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ZTH
Type: protein
Length: 694 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: STU0660
UniProt: Q5M539
Ligands: MG
Pockets: 8 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	STU0660	protein	347	45% helix, 14% strand	Q5M539

Ligands and binding sites

MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1175	0.85	0.86	126	MG
2	703	0.67	0.76	63	empty
3	214	0.53	0.77	27	empty
4	216	0.53	0.77	34	empty
5	65	0.45	0.83	19	MG

Interfaces

1 interface between chains.

A–B · 3235 Å² buried · 37 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 16 modified (engineered).

Compared structures

3ZTH · Crystal structure of Stu0660 of Streptococcus thermophilus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5M539
Elsewhere: RCSB PDB 3ZTH · PDBe 3ZTH · UniProt Q5M539

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