Research workbench
Solution structure of the ring finger-like domain of retinoblastoma binding protein-6 (RBBP6)
Analyse Solution structure of the ring finger-like domain of retinoblastoma binding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ZTG
- Type
- protein
- Length
- 184 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase RBBP6
- EC
- 6.3.2.-
- UniProt
- Q7Z6E9
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.55
Structure
solution nmr · 1 distinct chain · 27% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | E3 ubiquitin-protein ligase RBBP6 (EC 6.3.2.-) | protein | 92 | 27% helix, 11% strand | Q7Z6E9 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 206 | 0.55 | 0.78 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 856 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 3ZTG · Solution structure of the RING finger-like domain of Retinoblastoma Binding Protein-6… · the same entry in another collection · chain A against A, TM-score 1.00
- Q7Z6E9 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RBBP6 (Q7Z6E9) · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7Z6E9
- Elsewhere: RCSB PDB 3ZTG · PDBe 3ZTG · UniProt Q7Z6E9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.