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M.ACETIVORANS protoglobin F145W mutant

Analyse M.ACETIVORANS protoglobin F145W mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ZOM
Type: protein
Length: 382 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protoglobin
UniProt: Q8TLY9
Ligands: HEM, SO4
Pockets: 3 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 63% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protoglobin	protein	191	63% helix, 1% strand	Q8TLY9

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
SO4 · Sulfate ion · ion · chains A
GOL · Glycerol · additive · 3 copies · chains B, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	283	0.85	0.96	37	HEM
2	291	0.85	0.95	36	HEM
3	56	0.45	0.84	16	GOL

Interfaces

1 interface between chains.

A–B · 337 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

3ZOM · M.acetivorans protoglobin F145W mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TLY9
Elsewhere: RCSB PDB 3ZOM · PDBe 3ZOM · UniProt Q8TLY9

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