Research workbench
X-ray structure of E.COLI wrba in complex with FMN at 1.2 a resolution
Analyse X-ray structure of E.COLI wrba in complex with FMN at 1.2 a resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ZHO
- Type
- protein
- Length
- 373 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Flavoprotein wrba
- EC
- 1.6.5.2
- UniProt
- P0A8G6
- Ligands
- FMN
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Flavoprotein wrba (EC 1.6.5.2) | protein | 194 | 40% helix, 17% strand | P0A8G6 |
| B | Flavoprotein wrba (EC 1.6.5.2) | protein | 179 | 41% helix, 21% strand | P0A8G6 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 371 | 0.62 | 0.78 | 41 | FMN |
| 2 | 308 | 0.57 | 0.76 | 40 | FMN |
Interfaces
1 interface between chains.
- A–B · 895 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (nonstandard).
Compared structures
- 3ZHO · X-ray structure of E.coli Wrba in complex with FMN at 1.2 A resolution · the same entry in another collection · chain A against A, TM-score 1.00
- P0A8G6 · AlphaFold monomer V2.0 prediction for NAD(P)H dehydrogenase (quinone) (P0A8G6) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A8G6
- Elsewhere: RCSB PDB 3ZHO · PDBe 3ZHO · UniProt P0A8G6
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