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Microbacterium saccharophilum K-1 beta-fructofuranosidase mutant T47S/S200T/F447V/P500S

Analyse Microbacterium saccharophilum K-1 beta-fructofuranosidase mutant… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3WPY
Type: protein
Length: 1,614 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-fructofuranosidase
EC: 3.2.1.26
UniProt: Q8VW87
Pockets: 19 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Beta-fructofuranosidase (EC 3.2.1.26)	protein	538	15% helix, 37% strand	Q8VW87

Pockets

19 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	644	0.68	0.77	66	empty
2	446	0.66	0.79	46	empty
3	460	0.65	0.78	46	empty
4	455	0.64	0.77	41	empty
5	303	0.56	0.76	40	empty

Interfaces

2 interfaces between chains.

A–B · 453 Å² buried · 7 hydrogen bonds · protein-protein
B–C · 270 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

3WPY · Microbacterium saccharophilum K-1 beta-fructofuranosidase mutant T47S/S200T/F447V/P500S · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8VW87
Elsewhere: RCSB PDB 3WPY · PDBe 3WPY · UniProt Q8VW87

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