Research workbench

Crystal structure of GOX2253

Analyse Crystal structure of GOX2253 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3WJ7
Type: protein
Length: 990 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative oxidoreductase
UniProt: Q5FNR0
Ligands: HG
Pockets: 9 · best druggability 0.87

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Putative oxidoreductase	protein	330	44% helix, 17% strand	Q5FNR0

Ligands and binding sites

HG · Mercury (II) ion · metal · 6 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	855	0.87	0.90	102	empty
2	761	0.86	0.89	84	empty
3	475	0.83	0.90	54	empty
4	239	0.79	0.92	36	empty
5	379	0.79	0.88	51	HG

Interfaces

3 interfaces between chains.

B–C · 1212 Å² buried · 16 hydrogen bonds · protein-protein
A–B · 1209 Å² buried · 15 hydrogen bonds · protein-protein
A–C · 1182 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

3WJ7 · Crystal structure of gox2253 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5FNR0
Elsewhere: RCSB PDB 3WJ7 · PDBe 3WJ7 · UniProt Q5FNR0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.