Research workbench
P453H/I471T mutant of PB2 middle domain from influenza virus A/PUERTO RICO/8/34(H1N1) with M7GTP
Analyse P453H/I471T mutant of PB2 middle domain from influenza virus A/PUERTO… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3WI1
- Type
- protein
- Length
- 162 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Polymerase basic protein 2
- UniProt
- P03428
- Ligands
- MGT
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polymerase basic protein 2 | protein | 162 | 22% helix, 42% strand | P03428 |
Ligands and binding sites
- MGT · 7N-methyl-8-hydroguanosine-5'-triphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.43 | 0.76 | 18 | MGT |
Compared structures
- 3WI1 · P453H/I471T mutant of PB2 middle domain from influenza virus A/Puerto Rico/8/34(H1N1)… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03428
- Elsewhere: RCSB PDB 3WI1 · PDBe 3WI1 · UniProt P03428
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