Research workbench
X-ray-crystallographic structure of an RNase PO1 exhibiting anti-tumor activity
Analyse X-ray-crystallographic structure of an RNase PO1 exhibiting anti-tumor activity in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3WHO
- Type
- protein
- Length
- 303 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Guanyl-specific ribonuclease PO1
- EC
- 3.1.27.3
- UniProt
- P81762
Structure
x-ray diffraction · 1 distinct chain · 12% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Guanyl-specific ribonuclease PO1 (EC 3.1.27.3) | protein | 101 | 12% helix, 35% strand | P81762 |
Interfaces
2 interfaces between chains.
- A–C · 335 Ų buried · 4 hydrogen bonds · protein-protein
- A–B · 309 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 3WHO · X-ray-Crystallographic Structure of an RNase Po1 Exhibiting Anti-tumor Activity · the same entry in another collection · chain C against C, TM-score 1.00
- P81762 · AlphaFold monomer V2.0 prediction for guanyl-specific ribonuclease PO1 (P81762) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P81762
- Elsewhere: RCSB PDB 3WHO · PDBe 3WHO · UniProt P81762
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