Research workbench
Staphylococcus aureus ftsz bound with GTP-gamma-S
Analyse Staphylococcus aureus ftsz bound with GTP-gamma-S in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3WGN
- Type
- protein
- Length
- 608 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division protein ftsz
- UniProt
- P0A029
- Ligands
- GSP
- Pockets
- 8 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cell division protein ftsz | protein | 304 | 44% helix, 23% strand | P0A029 |
Ligands and binding sites
- GSP · 5'-guanosine-diphosphate-monothiophosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 243 | 0.59 | 0.80 | 40 | GSP |
| 2 | 207 | 0.59 | 0.81 | 37 | GSP |
| 3 | 288 | 0.57 | 0.77 | 43 | empty |
| 4 | 87 | 0.42 | 0.78 | 18 | empty |
| 5 | 78 | 0.39 | 0.78 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 426 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A029
- Elsewhere: RCSB PDB 3WGN · PDBe 3WGN · UniProt P0A029
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.