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Crystal structure of agrocybe cylindracea galectin mutant (N46A)

Analyse Crystal structure of agrocybe cylindracea galectin mutant (N46A) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3WG2
Type: protein
Length: 304 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Galactoside-binding lectin
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Galactoside-binding lectin	protein	152	3% helix, 57% strand	—

Ligands and binding sites

PGE · Triethylene glycol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	186	0.53	0.79	31	PGE

Interfaces

1 interface between chains.

A–B · 965 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

3WG2 · Crystal structure of Agrocybe cylindracea galectin mutant (N46A) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3WG2 · PDBe 3WG2

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