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Crystal structure analysis of eukaryotic translation initiation factor 5B structure II

Analyse Crystal structure analysis of eukaryotic translation initiation factor 5B… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3WBJ
Type: protein
Length: 445 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Eukaryotic translation initiation factor 5B
UniProt: P39730
Pockets: 4 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Eukaryotic translation initiation factor 5B	protein	445	33% helix, 27% strand	P39730

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	256	0.73	0.87	31	empty
2	341	0.57	0.76	50	empty
3	127	0.48	0.79	20	empty
4	50	0.25	0.74	15	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

3WBJ · Crystal structure analysis of eukaryotic translation initiation factor 5B structure II · the same entry in another collection · chain A against A, TM-score 1.00
P39730 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5B (P39730) · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39730
Elsewhere: RCSB PDB 3WBJ · PDBe 3WBJ · UniProt P39730

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